Peer-reviewed publications.

8 papers

• 2026Nature Methods

  Tunable hydrogel-based micropillar arrays for myelination studies

  Developed tunable micropillar arrays mimicking axon biomechanics to model myelination — supports multilayered compact myelin formation and enables drug screening for remyelination therapies.

  DOI: 10.1038/s41592-026-03048-3
• 2025npj Biological Physics and Mechanics

  Mechanical signatures in cancer metastasis

  Comprehensive review identifying mechanical signatures throughout the metastatic cascade and mechanobiology-based therapeutic interventions for cancer treatment.

  DOI: 10.1038/s44341-024-00007-x
• 2024Aging (Albany NY)

  Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity

  Large ARDD 2023 review synthesising AI, biomarkers, geroscience, and clinical longevity interventions.

  DOI: 10.18632/aging.206135
• 2023Science Advances

  Emergent mechanical control of vascular morphogenesis

  Tissue stiffness increases during vascular morphogenesis through emergent interactions between endothelial cells, fibroblasts, and ECM — YAP1 in fibroblasts is critical for vascular function.

  DOI: 10.1126/sciadv.adg9781
• 2023Advanced Science

  Endothelium and subendothelial matrix mechanics modulate cancer cell transendothelial migration

  Cancer cell extravasation depends on mechanical interactions between tumour cells, endothelium, and ECM — subendothelial stiffness helps shape metastatic organotropism.

  DOI: 10.1002/advs.202206554
• 2023Frontiers in Cell and Developmental Biology

  Mechanobiology in oncology: basic concepts and clinical prospects

  Review: mechanical alterations in stiffness and morphology are linked to cancer initiation and dissemination — advanced imaging and lab-on-chip enable personalised tumour biomechanics.

  DOI: 10.3389/fcell.2023.1239749
• 2023Materials Today Bio

  Stromal cells regulate mechanics of tumour spheroid

  Stromal cells alter cancer spheroid-matrix interactions — inverse relationship between invasiveness and collagen deformation, mediated by inflammatory cytokines.

  DOI: 10.1016/j.mtbio.2023.100821
• 2023Frontiers in Aging Neuroscience

  Hippocampus of the APPNL-G-F mouse model of Alzheimer's disease exhibits region-specific tissue softening concomitant with elevated astrogliosis

  Alzheimer's hippocampal regions are significantly softer than controls — tissue softening coincides with astrocyte reactivity and is associated with neuronal vulnerability.

  DOI: 10.3389/fnagi.2023.1212212